Yuelin Wu

Discovery, Synthesis, and Biological Evaluation of Orally Active Pyrrolidone Derivatives as Novel Inhibitors of p53–MDM2 Protein–Protein Interaction

Chunlin Zhuang, Zhenyuan Miao, Lingjian Zhu et al. · Journal of Medicinal Chemistry · 2012 · 128 citations

Pharmacotherapy, Chemistry, Chemical Biology +19

Double-Edged Swords as Cancer Therapeutics: Novel, Orally Active, Small Molecules Simultaneously Inhibit p53–MDM2 Interaction and the NF-κB Pathway

Chunlin Zhuang, Zhenyuan Miao, Yuelin Wu et al. · Journal of Medicinal Chemistry · 2014 · 48 citations

Double-edged Swords, Cancer Biology, Pharmaceutical Chemistry +23

Design, synthesis and biological activity of piperlongumine derivatives as selective anticancer agents

Yuelin Wu, Min Xiao, Chunlin Zhuang et al. · European Journal of Medicinal Chemistry · 2014 · 45 citations

Biological Activity, Medicinal Chemistry, Natural Sciences +11

A New Strategy To Improve the Metabolic Stability of Lactone: Discovery of (20<i>S</i>,21<i>S</i>)-21-Fluorocamptothecins as Novel, Hydrolytically Stable Topoisomerase I Inhibitors

Zhenyuan Miao, Lingjian Zhu, Guoqiang Dong et al. · Journal of Medicinal Chemistry · 2013 · 42 citations

Chemical Biology, Pharmaceutical Chemistry, α-Fluoro Ether/lactone Replacement +16

Quercetin prevents the ferroptosis of OPCs by inhibiting the Id2/transferrin pathway

Yeyang Wang, Wenjun Li, Mingsen Wang et al. · Chemico-Biological Interactions · 2023 · 25 citations

Biochemistry, Medicine, Natural Sciences +5