Lingjian Zhu

Discovery, Synthesis, and Biological Evaluation of Orally Active Pyrrolidone Derivatives as Novel Inhibitors of p53–MDM2 Protein–Protein Interaction

Chunlin Zhuang, Zhenyuan Miao, Lingjian Zhu et al. · Journal of Medicinal Chemistry · 2012 · 132 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

A New Strategy To Improve the Metabolic Stability of Lactone: Discovery of (20<i>S</i>,21<i>S</i>)-21-Fluorocamptothecins as Novel, Hydrolytically Stable Topoisomerase I Inhibitors

Zhenyuan Miao, Lingjian Zhu, Guoqiang Dong et al. · Journal of Medicinal Chemistry · 2013 · 43 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Structure–activity relationship and antitumor activity of thio-benzodiazepines as p53–MDM2 protein–protein interaction inhibitors

Zizhao Guo, Chunlin Zhuang, Lingjian Zhu et al. · European Journal of Medicinal Chemistry · 2012 · 40 citations · Full text

Medicine, Medicinal Chemistry, Oncology +14

Synthesis and Biological Evaluation of Novel Homocamptothecins Conjugating with Dihydropyrimidine Derivatives as Potent Topoisomerase I Inhibitors

Lingjian Zhu, Pengfei Cheng, Jianzhong Yao et al. · Archiv der Pharmazie · 2011 · 34 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53–MDM2 protein–protein interaction

Chunlin Zhuang, Zhenyuan Miao, Lingjian Zhu et al. · European Journal of Medicinal Chemistry · 2011 · 28 citations

Medicine, Medicinal Chemistry, Oncology +7