IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation

Matija Hedl, Jie Yan, Clara Abraham

Cell Reports

Identification of microRNA transcriptome involved in human natural killer cell activation

Xin Liu, Yanli Wang, Qian Sun, +4

Immunology Letters

Natural Killer CellsFunctional GenomicsImmunologyLong Non-coding RnaMicrorna Transcriptome +8

T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation

Jie Yan, Surya Pandey, Betsy Barnes, +2

Cell Reports

An inflammatory bowel disease–risk variant in INAVA decreases pattern recognition receptor–induced outcomes

Jie Yan, Matija Hedl, Clara Abraham

Journal of Clinical Investigation

Chronic Inflammatory DiseasesInflammatory Lung DiseaseInnate Immune SystemImmunologyGastroenterology +22

Eosinophils from Murine Lamina Propria Induce Differentiation of Naïve T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid

Chen Honghu, Aihua Sun, David M. Ojcius, +6

PLoS ONE

Lymphocyte DevelopmentT-regulatory CellNaïve T CellsImmunologyImmune Regulation +17

IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and <i>IRF5</i> Immune-Mediated Disease Risk Variants Modulate This Outcome

Matija Hedl, Jie Yan, Heiko Witt, +1

The Journal of Immunology

Myeloid Cell Expression of LACC1 Is Required for Bacterial Clearance and Control of Intestinal Inflammation

Jung‐Woo Kang, Jie Yan, Kishu Ranjan, +3

Gastroenterology

InflammationLacc1 Is RequiredMucosal ImmunologyImmunologyMyeloid Cell Expression +5

INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling

Phi Luong, Matija Hedl, Jie Yan, +9

eLife

Reducing IRF5 expression attenuates colitis in mice, but impairs the clearance of intestinal pathogens

Surya Pandey, Jie Yan, Jerrold R. Turner, +1

Mucosal Immunology

InflammationIrf5 ExpressionIntestinal PathogensMucosal ImmunologyPathogenesis +8

Clinical and CT diagnosis of 50 cases of Chlamydia psittaci pneumonia

Jing Wu, Junping Pan, Chengyu Han, +5

Quantitative Imaging in Medicine and Surgery