Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü, +23

Cancer Cell

Hematological MalignancySomatic VariantHypermethylation PhenotypeMedicineGenetics +8

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

José M. Polo, Susanna Liu, María E. Figueroa, +12

Nature Biotechnology

Origin InfluencesInduced Pluripotent Stem CellDevelopmental BiologyPluripotent Stem CellsMedicine +8

DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

María E. Figueroa, Sanne Lugthart, Yushan Li, +14

Cancer Cell

Hematological MalignancyChromatinEpigenetic ChangeGeneticsDna Methylation +8

MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

María E. Figueroa, Lucy Skrabanek, Yushan Li, +10

Blood

RBM15 facilitates laryngeal squamous cell carcinoma progression by regulating TMBIM6 stability through IGF2BP3 dependent

Xin Wang, Linli Tian, Yushan Li, +8

Journal of Experimental & Clinical Cancer Research

DNA Hydroxymethylation Profiling Reveals that WT1 Mutations Result in Loss of TET2 Function in Acute Myeloid Leukemia

Raajit K. Rampal, Altuna Alkalin, Jozef Madžo, +31

Cell Reports

Water use efficiency and sustainability of different long-term crop rotation systems in the Loess Plateau of China

Mingbin Huang, Mingan Shao, Lu Zhang, +1

Soil and Tillage Research

Water Use EfficiencyWater AvailabilityEngineeringWater ResourcesDrought +10

Integrated genetic and epigenetic analysis of childhood acute lymphoblastic leukemia

María E. Figueroa, Shann-Ching Chen, Anna Andersson, +7

Journal of Clinical Investigation

Hematological MalignancyChromatinEpigenetic ChangeGeneticsDna Methylation +13

Association between different insulin resistance surrogates and all-cause mortality in patients with coronary heart disease and hypertension: NHANES longitudinal cohort study

Xin-Zheng Hou, Yanfei Lv, Yushan Li, +9

Cardiovascular Diabetology

Selenium enhances iron plaque formation by elevating the radial oxygen loss of roots to reduce cadmium accumulation in rice (Oryza sativa L.)

Gaoxiang Huang, Changfeng Ding, Yushan Li, +2

Journal of Hazardous Materials

Radial Oxygen LossEngineeringBotanyCadmium AccumulationEnvironmental Engineering +7