DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

María E. Figueroa, Sanne Lugthart, Yushan Li, +14

Cancer Cell

Hematological MalignancyChromatinEpigenetic ChangeGeneticsDna Methylation +8

MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

María E. Figueroa, Lucy Skrabanek, Yushan Li, +10

Blood

eIF4E is a central node of an RNA regulon that governs cellular proliferation

Biljana Čuljković, Ivan Topisirović, Lucy Skrabanek, +2

The Journal of Cell Biology

EngineeringCell CycleTranscriptional RegulationCapped MrnasLong Non-coding Rna +15

eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3′UTR

Biljana Čuljković, Ivan Topisirović, Lucy Skrabanek, +2

The Journal of Cell Biology

PDZBase: a protein–protein interaction database for PDZ-domains

Thijs Beuming, Lucy Skrabanek, Masha Y. Niv, +2

Bioinformatics

Structural BioinformaticsMolecular BiologySequence MotifProtein FoldingProteomics +14

Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease

Yoshiyuki Ban, David A. Greenberg, Erlinda Concepcion, +3

Proceedings of the National Academy of Sciences

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1

Sanne Lugthart, María E. Figueroa, Eric M. Bindels, +9

Blood

Stability of Eukaryotic Translation Initiation Factor 4E mRNA Is Regulated by HuR, and This Activity Is Dysregulated in Cancer

Ivan Topisirović, Nadeem Siddiqui, Slobodanka Orolicki, +4

Molecular and Cellular Biology

Activity IsMolecular BiologyTumor BiologyCell RegulationEif4e Levels +14

Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features

María E. Figueroa, Bas J. Wouters, Lucy Skrabanek, +10

Blood

Estimation of Synteny Conservation and Genome Compaction Between Pufferfish (<i>Fugu</i>) and Human

Aoife McLysaght, Anton J. Enright, Lucy Skrabanek, +1

Yeast