Liling Liu

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake et al. · Journal of Medicinal Chemistry · 2021 · 159 citations

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties

Peter S. Dragovich, Thomas H. Pillow, Robert A. Blake et al. · Journal of Medicinal Chemistry · 2021 · 140 citations

A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment

Alessia Balestrini, Victory Joseph, Michelle Dourado et al. · The Journal of Experimental Medicine · 2021 · 127 citations · Full text

Inflammation, Asthma, Trpa1 Inhibitor +15

Utility of Intersystem Extrapolation Factors in Early Reaction Phenotyping and the Quantitative Extrapolation of Human Liver Microsomal Intrinsic Clearance Using Recombinant Cytochromes P450

Yuan Chen, Liling Liu, Khanh Hoang Nguyen et al. · Drug Metabolism and Disposition · 2010 · 98 citations

Overcoming Preclinical Safety Obstacles to Discover (<i>S</i>)-<i>N</i>-((1,2,3,5,6,7-Hexahydro-<i>s</i>-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5<i>H</i>-pyrazolo[5,1-<i>b</i>][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor

Christopher McBride, Lynnie Trzoss, Davide Povero et al. · Journal of Medicinal Chemistry · 2022 · 65 citations · Full text