Xueyan Wang

Discovery of 5-[5-Fluoro-2-oxo-1,2- dihydroindol-(3<i>Z</i>)-ylidenemethyl]-2,4- dimethyl-1<i>H</i>-pyrrole-3-carboxylic Acid (2-Diethylaminoethyl)amide, a Novel Tyrosine Kinase Inhibitor Targeting Vascular Endothelial and Platelet-Derived Growth Factor Receptor Tyrosine Kinase

Li Sun, Chris Liang, Sheri Shirazian et al. · Journal of Medicinal Chemistry · 2003 · 518 citations · Full text

Chemoprevention Strategy, Weakly Basic Analogues, Pharmacotherapy +20

A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo.

James G. Christensen, Randall Schreck, Jon Burrows et al. · PubMed · 2003 · 497 citations

Cancer Biology, Tumor Biology, C-met Kinase +20

Potent and selective inhibitors of the Met [hepatocyte growth factor/scatter factor (HGF/SF) receptor] tyrosine kinase block HGF/SF-induced tumor cell growth and invasion.

Xueyan Wang, Phuong Le, Congxin Liang et al. · PubMed · 2003 · 114 citations

Pathology, Selective Inhibitors, Tumor Biology +16

Growth hormone promoted tyrosyl phosphorylation of growth hormone receptors in murine 3T3-F442A fibroblasts and adipocytes

Carol M. Foster, Jules A. Shafer, Frank W. Rozsa et al. · Biochemistry · 1988 · 111 citations

Human Growth, Immunology, Mr 114,000 +16

Efficient Palladium-Catalyzed C–H Fluorination of C(sp3)–H Bonds: Synthesis of β-Fluorinated Carboxylic Acids

Qihua Zhu, Dezhong Ji, Tingting Liang et al. · Organic Letters · 2015 · 87 citations