Pu Wang

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu, Hui Yang, Ying Liu et al. · Cancer Cell · 2011 · 2.8K citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

Glioma-Derived Mutations in <i>IDH1</i> Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α

Shimin Zhao, Yan Lin, Wei Xu et al. · Science · 2009 · 1.1K citations

Medicine, Molecular Biology, Oncology +17

iAMP-2L: A two-level multi-label classifier for identifying antimicrobial peptides and their functional types

Xuan Xiao, Pu Wang, Wei‐Zhong Lin et al. · Analytical Biochemistry · 2013 · 555 citations

Life Sciences, Bioinformatics, Microbiology +12

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

Pu Wang, Qiongzhu Dong, C. Zhang et al. · Oncogene · 2012 · 389 citations

Medicine, Genetics, Oncology +14

ErbB4 in parvalbumin-positive interneurons is critical for neuregulin 1 regulation of long-term potentiation

Yongjun Chen, Meng Zhang, Dong‐Min Yin et al. · Proceedings of the National Academy of Sciences · 2010 · 243 citations

Life Sciences, Neurobiology, Neuroscience +17