PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

Haidong Tang, Yong Liang, Robert A. Anders, +18

Journal of Clinical Investigation

PD-1 Restrains Radiotherapy-Induced Abscopal Effect

Sean S. Park, Haidong Dong, Xin Liu, +7

Cancer Immunology Research

Cancer ImmunosurveillanceAbscopal EffectRadiation TherapyMedicineImmunology +11

CX3CR1 identifies PD-1 therapy–responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy

Yiyi Yan, Siyu Cao, Xin Liu, +12

JCI Insight

ImmunologyAbcb1 TransporterCd4 T Cell ResponsesImmune Cell TherapyImmunotherapy +14

ADAM10 and ADAM17 cleave PD-L1 to mediate PD-(L)1 inhibitor resistance

Jacob J. Orme, Khalid Jazieh, Tiancheng Xie, +13

OncoImmunology

Inhibitor ResistanceTumor BiologyMedicinal ChemistryInhibitory ActivitySoluble Pd-l1 +13

PD-L1 tumor-intrinsic signaling and its therapeutic implication in triple-negative breast cancer

Chunhua Chen, Shiheng Li, Junli Xue, +6

JCI Insight

NKG7 Is a T-cell–Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy

Ti Wen, Whitney Barham, Ying Li, +26

Cancer Immunology Research

BRAFV600E-induced, tumor intrinsic PD-L1 can regulate chemotherapy-induced apoptosis in human colon cancer cells and in tumor xenografts

Daofu Feng, Bo Qin, Krishnendu Pal, +7

Oncogene

Tumor XenograftsMedicineTumor Intrinsic Pd-l1ImmunologyCell Death +7

Expression of PD-1 on CD4+ T cells in peripheral blood associates with poor clinical outcome in non-small cell lung cancer

Hong Zheng, Xin Liu, Jianhong Zhang, +7

Oncotarget

Advanced NsclcPrognostic BiomarkersCancer ImmunosurveillancePeripheral Blood AssociatesPoor Clinical Outcome +13

DPEP1 is a direct target of miR-193a-5p and promotes hepatoblastoma progression by PI3K/Akt/mTOR pathway

Xichun Cui, Xin Liu, Qicai Han, +10

Cell Death and Disease

DNAzyme-Derived Aptamer Reversely Regulates the Two Types of Enzymatic Activities of Covalent–Organic Frameworks for the Colorimetric Analysis of Uranium

Li Zhang, Quan‐Gen Tan, Sai Jin Xiao, +6

Analytical Chemistry