Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

Hanna Rajala, Samuli Eldfors, Heikki Kuusanmäki, +17

Blood

CX3CR1 identifies PD-1 therapy–responsive CD8+ T cells that withstand chemotherapy during cancer chemoimmunotherapy

Yiyi Yan, Siyu Cao, Xin Liu, +12

JCI Insight

ImmunologyAbcb1 TransporterCd4 T Cell ResponsesImmune Cell TherapyImmunotherapy +14

NKG7 Is a T-cell–Intrinsic Therapeutic Target for Improving Antitumor Cytotoxicity and Cancer Immunotherapy

Ti Wen, Whitney Barham, Ying Li, +26

Cancer Immunology Research

Therapeutic plasma exchange clears circulating soluble PD-L1 and PD-L1-positive extracellular vesicles

Jacob J. Orme, Elizabeth Ann L. Enninga, Fabrice Lucien-Matteoni, +12

Journal for ImmunoTherapy of Cancer

Targeting B7-H1 (PD-L1) sensitizes cancer cells to chemotherapy

Xiaosheng Wu, Yanli Li, Xin Liu, +11

Heliyon

Chemo-immunotherapy combination after PD-1 inhibitor failure improves clinical outcomes in metastatic melanoma patients

Jesus Vera Aguilera, Jonas Paludo, Robert R. McWilliams, +10

Melanoma Research

Lymphocyte-to-monocyte ratio is associated with survival in pembrolizumab-treated metastatic melanoma patients

Jarrett Failing, Yiyi Yan, Luis F. Porrata, +1

Melanoma Research

Lymphocyte-to-monocyte RatioBaseline LmrPrognostic BiomarkersMedicineMelanoma +10

β-glucan and anisodamine can enhance the immersion immune efficacy of inactivated cyprinid herpesvirus 2 vaccine in Carassius auratus gibelio

Yiyi Yan, Xingchen Huo, Taoshan Ai, +1

Fish & Shellfish Immunology

VaccinationCarassius Auratus GibelioVeterinary VaccineImmersion Immune EfficacyVaccine Development +6

CpG-induced antitumor immunity requires IL-12 in expansion of effector cells and down-regulation of PD-1

Peng Yin, Xin Liu, Aaron S. Mansfield, +4

Oncotarget

ImmunologyImmune RegulationImmunologic MechanismImmunotherapeuticsCd4 T Cell Responses +19

Artemis interacts with the Cul4A-DDB1 ^DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27

Yiyi Yan, Xiaoshan Zhang, Randy J. Legerski

Cell Cycle