Rose Marwood

3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as High Affinity, Selective, and Orally Bioavailable h5-HT_2A Receptor Antagonists

Michael Rowley, David J. Hallett, Simon Goodacre et al. · Journal of Medicinal Chemistry · 2001 · 109 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange

Sandrine Guillard, Paulina Kolasinska-Zwierz, J.E. Debreczeni et al. · Nature Communications · 2017 · 108 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe

Nicolas Béry, Sandrine Legg, J.E. Debreczeni et al. · Nature Communications · 2019 · 96 citations · Full text

Medicine, Molecular Biology, Oncology +17

4-(Phenylsulfonyl)piperidines:  Novel, Selective, and Bioavailable 5-HT_2AReceptor Antagonists

Stephen R. Fletcher, Frank Burkamp, Peter Blurton et al. · Journal of Medicinal Chemistry · 2001 · 51 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Preclinical Evaluation of MEDI0641, a Pyrrolobenzodiazepine-Conjugated Antibody–Drug Conjugate Targeting 5T4

Jay Harper, Christopher Lloyd, Nazzareno Dimasi et al. · Molecular Cancer Therapeutics · 2017 · 47 citations · Full text

Pharmacy, Oncology, Pharmacology +17