David J. Hallett

Evidence for a Significant Role of α3-Containing GABA_AReceptors in Mediating the Anxiolytic Effects of Benzodiazepines

Rebecca Dias, Wayne F. A. Sheppard, Rosa Fradley et al. · Journal of Neuroscience · 2005 · 246 citations · Full text

Medicine, Pharmacology, Psychiatry +15

Imidazo[1,2<i>-a</i>]pyrimidines as Functionally Selective and Orally Bioavailable GABA_Aα2/α3 Binding Site Agonists for the Treatment of Anxiety Disorders

Simon Goodacre, Leslie J. Street, David J. Hallett et al. · Journal of Medicinal Chemistry · 2005 · 132 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

8-Fluoroimidazo[1,2-a]pyridine: Synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABAA receptor

Alexander C. Humphries, Emanuela Gancia, Myra T. Gilligan et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 115 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as High Affinity, Selective, and Orally Bioavailable h5-HT_2A Receptor Antagonists

Michael Rowley, David J. Hallett, Simon Goodacre et al. · Journal of Medicinal Chemistry · 2001 · 109 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Differential contribution of GABA _A receptor subtypes to the anticonvulsant efficacy of benzodiazepine site ligands

Rosa Fradley, Martin R. Guscott, Sharlene Bull et al. · Journal of Psychopharmacology · 2006 · 55 citations

Medicine, Neuroscience, Pharmacology +14