Alexander C. Humphries

Evidence for a Significant Role of α3-Containing GABA_AReceptors in Mediating the Anxiolytic Effects of Benzodiazepines

Rebecca Dias, Wayne F. A. Sheppard, Rosa Fradley et al. · Journal of Neuroscience · 2005 · 244 citations · Full text

Anesthetic Mechanism, Psychopharmacology, Pharmacotherapy +19

8-Fluoroimidazo[1,2-a]pyridine: Synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABAA receptor

Alexander C. Humphries, Emanuela Gancia, Myra T. Gilligan et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 113 citations · Full text

Bioisosteric Replacement, Allosteric Modulator Ligand, Medicinal Chemistry +12

Total synthesis of the protein phosphatase inhibitor okadaic acid

Steven V. Ley, Alexander C. Humphries, Holger Eick et al. · Journal of the Chemical Society Perkin Transactions 1 · 1998 · 65 citations

Medicinal Chemistry, Biosynthesis, Bioorganic Chemistry +11

4-Fluorosulfonylpiperidines: Selective 5-HT2A ligands for the treatment of insomnia

L. Rebecca Fish, Myra T. Gilligan, Alexander C. Humphries et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 37 citations · Full text

Medicinal Chemistry, Medicine, Natural Sciences +7

The Asymmetric Maitland−Japp Reaction and Its Application to the Construction of the C1−C19 <i>Bis</i>-pyran Unit of Phorboxazole B

Paul A. Clarke, Soraia Santos, Nimesh Mistry et al. · Organic Letters · 2011 · 31 citations