William G. Payne

Impact of WIN site inhibitor on the WDR5 interactome

Alissa D. Guarnaccia, Kristie L. Rose, Jing Wang et al. · Cell Reports · 2021 · 75 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Discovery of WD Repeat-Containing Protein 5 (WDR5)–MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design

Selena Chacón Simon, Feng Wang, Lance R. Thomas et al. · Journal of Medicinal Chemistry · 2020 · 73 citations · Full text

Medicine, Molecular Biology, Oncology +15

Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5–MYC Protein–Protein Interaction

Jonathan D. Macdonald, Selena Chacón Simon, Changho Han et al. · Journal of Medicinal Chemistry · 2019 · 64 citations · Full text

Medicine, Medicinal Chemistry, Oncology +15

Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core

Jianhua Tian, Kevin B. Teuscher, Erin R. Aho et al. · Journal of Medicinal Chemistry · 2019 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Dethiobiotin Synthetase: The Carbonylation of 7,8-Diaminononanoic Acid Proceeds Regiospecifically via the N7-Carbamate

Katharine J. Gibson, George H. Lorimer, Alan R. Rendina et al. · Biochemistry · 1995 · 35 citations

Life Sciences, Biochemistry, Chemistry +5