Alexander V. Kel’in

Multivalent <i>N</i>-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

Jayaprakash K. Nair, Jennifer L. S. Willoughby, Amy Chan et al. · Journal of the American Chemical Society · 2014 · 1.1K citations

Pharmacy, Pharmaceutics, Pharmacology +17

An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia

Alfica Sehgal, Scott Barros, Lacramioara Ivanciu et al. · Nature Medicine · 2015 · 297 citations

Medicine, Hematology, Molecular Biology +12

siRNA Conjugates Carrying Sequentially Assembled Trivalent <i>N-</i>Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing <i>In Vivo</i> in Hepatocytes

Shigeo Matsuda, Kristofer Keiser, Jayaprakash K. Nair et al. · ACS Chemical Biology · 2015 · 213 citations

Pharmacy, Molecular Biology, Pharmacology +17

A Novel 1,2‐Migration of Acyloxy, Phosphatyloxy, and Sulfonyloxy Groups in Allenes: Efficient Synthesis of Tri‐ and Tetrasubstituted Furans

Anna W. Sromek, Alexander V. Kel’in, Vladimir Gevorgyan · Angewandte Chemie International Edition · 2004 · 193 citations

Natural Sciences, Chemistry, Catalysis +12

1,2‐Migration of the Thio Group in Allenyl Sulfides: Efficient Synthesis of 3‐Thio‐Substituted Furans and Pyrroles

Joseph T. Kim, Alexander V. Kel’in, Vladimir Gevorgyan · Angewandte Chemie International Edition · 2003 · 161 citations

Natural Sciences, Chemistry, Medicinal Chemistry +5