Quantitative Profiling Method for Oxylipin Metabolome by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry

Jun Yang, Kara Schmelzer, Katrin Georgi, +1

Analytical Chemistry

Soluble epoxide hydrolase and epoxyeicosatrienoic acids modulate two distinct analgesic pathways

Bora İnceoğlu, Steven L. Jinks, Arzu Ulu, +7

Proceedings of the National Academy of Sciences

Pain MedicineLipid PeroxidationEpoxyeicosatrienoic AcidsNeuropathic PainMolecular Pain +19

Individual Variation in Lipidomic Profiles of Healthy Subjects in Response to Omega-3 Fatty Acids

Malin L. Nording, Jun Yang, Katrin Georgi, +7

PLoS ONE

Serum oxylipin profiles in IgA nephropathy patients reflect kidney functional alterations

Angela M. Zivkovic, Jun Yang, Katrin Georgi, +7

Metabolomics

UrologyRenal FunctionMedicineKidney FailurePhysiology +9

Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen

Aurélie Mallinger, Simon Crumpler, Mark Pichowicz, +29

Journal of Medicinal Chemistry

Identification and Optimization of an Aminoalcohol-Carbazole Series with Antimalarial Properties

Jérôme Molette, Julie Routier, Nada Abla, +9

ACS Medicinal Chemistry Letters

Drug TargetBioorganic ChemistryAntiparasitic AgentMalariaParasite Genomics +15

Multidimensional On-Line SPE for Undisturbed LC-MS-MS Analysis of Basic Drugs in Biofluids

Katrin Georgi, Karl‐Siegfried Boos

Chromatographia

EngineeringUndisturbed Lc-ms-ms AnalysisMedicineBioanalysisMass Spectrometry +12

Altered Soluble Epoxide Hydrolase Gene Expression and Function and Vascular Disease Risk in the Stroke-Prone Spontaneously Hypertensive Rat

Mandi J. Corenblum, Vance E. Wise, Katrin Georgi, +3

Hypertension

Multi-Well Array Culture of Primary Human Hepatocyte Spheroids for Clearance Extrapolation of Slowly Metabolized Compounds

Lena Preiss, Volker M. Lauschke, Katrin Georgi, +1

The AAPS Journal

HepatologyBiochemistrySlowly Metabolized CompoundsMedicineLiver Physiology +9

Considerations for Human <scp>ADME</scp> Strategy and Design Paradigm Shift(s) – An Industry White Paper

Graeme Young, Douglas K. Spracklin, Alexander D. James, +16

Clinical Pharmacology & Therapeutics