Heying Pei

Millepachine, a novel chalcone, induces G 2 /M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo

Wenshuang Wu, Haoyu Ye, Li Wan et al. · Carcinogenesis · 2013 · 100 citations

Chemoprevention Strategy, Apoptosis, Cell Death +22

Alkaloids from Black Pepper (<i>Piper nigrum</i> L.) Exhibit Anti-Inflammatory Activity in Murine Macrophages by Inhibiting Activation of NF-κB Pathway

Heying Pei, Linlin Xue, Minghai Tang et al. · Journal of Agricultural and Food Chemistry · 2020 · 81 citations

The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin

Jianhong Yang, Wei Yan, Yamei Yu et al. · Journal of Biological Chemistry · 2018 · 67 citations · Full text

Protein Chemistry, Biochemistry, Compound Millepachine +9

Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect

Jianhong Yang, Yamei Yu, Yong Li et al. · Science Advances · 2021 · 62 citations · Full text

Structural exploration, synthesis and pharmacological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives as iNOS inhibitors against inflammatory diseases

Liang Ma, Heying Pei, Lei Lei et al. · European Journal of Medicinal Chemistry · 2014 · 47 citations · Full text

Medicinal Chemistry, Inos Inhibitors, Diversity Oriented Synthesis +9