Jared Pitts

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice

Andrea J. Pruijssers, Amelia S. George, Alexandra Schäfer et al. · Cell Reports · 2020 · 530 citations · Full text

Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine <i>C</i>-Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV

Richard L. Mackman, Hon C. Hui, Michel Perron et al. · Journal of Medicinal Chemistry · 2021 · 79 citations · Full text

GNF-2 Inhibits Dengue Virus by Targeting Abl Kinases and the Viral E Protein

Margaret J. Clark, Chandra Miduturu, Aaron G. Schmidt et al. · Cell chemical biology · 2016 · 74 citations · Full text

Abl Kinases, Viral E Protein, Molecular Virology +8

Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants

Jared Pitts, Jiani Li, Jason K. Perry et al. · Antimicrobial Agents and Chemotherapy · 2022 · 74 citations · Full text

Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells

Ruidong Li, Albert Liclican, Yili Xu et al. · Antimicrobial Agents and Chemotherapy · 2021 · 61 citations · Full text