Dieter Saur

Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

Sebastian Mueller, Thomas Engleitner, Roman Maresch et al. · Nature · 2018 · 431 citations · Full text

Pancreatic Cancer, Evolutionary Routes, Medicine +4

Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase

Dietrich Alexander Ruess, Guus J.J.E. Heynen, Katrin J. Ciecielski et al. · Nature Medicine · 2018 · 363 citations

Tumor Biology, Mutant Kras-driven Cancers, Cancer Cell Biology +4

Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer

Stefan Eser, Nina Reiff, Marlena Messer et al. · Cancer Cell · 2013 · 354 citations

Tumor Biology, Signal Transduction, Signaling Pathway +11

E-Cadherin Regulates Metastasis of Pancreatic Cancer In Vivo and Is Suppressed by a SNAIL/HDAC1/HDAC2 Repressor Complex

Johannes von Burstin, Stefan Eser, Mariel C. Paul et al. · Gastroenterology · 2009 · 349 citations

Tumor Biology, Signaling Pathway, Snail/hdac1/hdac2 Repressor Complex +11

IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality

Hong Zhang, Patrick Neuhöfer, Liang Song et al. · Journal of Clinical Investigation · 2013 · 293 citations · Full text