Roman Maresch

Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

Sebastian Mueller, Thomas Engleitner, Roman Maresch et al. · Nature · 2018 · 445 citations · Full text

Medicine, Molecular Genetics, Oncology +10

PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis

Tim Wartewig, Zsuzsanna Kurgyis, Selina J. Keppler et al. · Nature · 2017 · 246 citations

Medicine, Cancer Biology, Oncology +13

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

Julia Weber, Rupert Öllinger, Mathias Friedrich et al. · Proceedings of the National Academy of Sciences · 2015 · 194 citations · Full text

Life Sciences, Genetics, Oncology +17

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

Roman Maresch, Sebastian Mueller, Christian Veltkamp et al. · Nature Communications · 2016 · 173 citations · Full text

Life Sciences, Biotechnology, Genetics +17

Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment

Chiara Falcomatà, Stefanie Bärthel, Sebastian A. Widholz et al. · Nature Cancer · 2022 · 105 citations · Full text

Medicine, Cancer Biology, Oncology +17