Sebastian A. Widholz

Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

Krushna C. Patra, Yasutaka Kato, Yusuke Mizukami et al. · Nature Cell Biology · 2018 · 198 citations

Medicine, Molecular Biology, Oncology +14

Genome‐wide cooperation of EMT transcription factor ZEB1 with YAP and AP‐1 in breast cancer

Nora Feldker, Fulvia Ferrazzi, Harald Schuhwerk et al. · The EMBO Journal · 2020 · 162 citations · Full text

Medicine, Genetics, Molecular Biology +11

Copy number variation of two separate regulatory regions upstream of <i>SOX9</i> causes isolated 46,XY or 46,XX disorder of sex development

Gwang-Jin Kim, Elisabeth Sock, Astrid Buchberger et al. · Journal of Medical Genetics · 2015 · 109 citations

Life Sciences, Genetics, Molecular Genetics +17

Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment

Chiara Falcomatà, Stefanie Bärthel, Sebastian A. Widholz et al. · Nature Cancer · 2022 · 105 citations · Full text

Medicine, Cancer Biology, Oncology +17

Non-canonical functions of SNAIL drive context-specific cancer progression

Mariel C. Paul, Christian Schneeweis, Chiara Falcomatà et al. · Nature Communications · 2023 · 28 citations · Full text

Medicine, Cancer Biology, Oncology +12