Sebastian A. Widholz

Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism

Krushna C. Patra, Yasutaka Kato, Yusuke Mizukami et al. · Nature Cell Biology · 2018 · 195 citations

Pka-mediated Sik Suppression, Signal Transduction, Signaling Pathway +11

Genome‐wide cooperation of <scp>EMT</scp> transcription factor <scp>ZEB</scp> 1 with <scp>YAP</scp> and <scp>AP</scp> ‐1 in breast cancer

Nora Feldker, Fulvia Ferrazzi, Harald Schuhwerk et al. · The EMBO Journal · 2020 · 155 citations · Full text

Copy number variation of two separate regulatory regions upstream of <i>SOX9</i> causes isolated 46,XY or 46,XX disorder of sex development

Gwang-Jin Kim, Elisabeth Sock, Astrid Buchberger et al. · Journal of Medical Genetics · 2015 · 108 citations

Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment

Chiara Falcomatà, Stefanie Bärthel, Sebastian A. Widholz et al. · Nature Cancer · 2022 · 101 citations · Full text

Cancer Immunosurveillance, Pancreatic Cancer, Selective Multi-kinase Inhibition +9

Non-canonical functions of SNAIL drive context-specific cancer progression

Mariel C. Paul, Christian Schneeweis, Chiara Falcomatà et al. · Nature Communications · 2023 · 26 citations · Full text