Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

Michal Bassani‐Sternberg, Eva Bräunlein, Richard Klar, +16

Nature Communications

CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

Julia Weber, Rupert Öllinger, Mathias Friedrich, +28

Proceedings of the National Academy of Sciences

EngineeringGeneticsCrispr/cas9 Somatic Multiplex-mutagenesisTumor BiologyCrispr +14

Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS

Detian Yuan, Shan Huang, Emanuel Berger, +40

Cancer Cell

Chronic Mitochondrial DysfunctionMitochondrial FunctionBiliary CancerLiver PhysiologyImmunology +7

Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice

Roman Maresch, Sebastian Mueller, Christian Veltkamp, +26

Nature Communications

Hypofractionated Irradiation Has Immune Stimulatory Potential and Induces a Timely Restricted Infiltration of Immune Cells in Colon Cancer Tumors

Benjamin Frey, Michael Rückert, Julia Weber, +7

Frontiers in Immunology

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer

Roland Rad, Lena Rad, Wei Wang, +42

Nature Genetics

Knockout MousePancreatic CancerOncogenic AgentGeneticsCancer Genomics +7

Cocarcinogens of the diterpene ester type fromCroton flavens L. and esophageal cancer in Curaçao

Julia Weber, E. Hecker

Cellular and Molecular Life Sciences

Esophageal CancerMedicineSecondary MetaboliteToxicologyPhytochemistry +1

A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes

Jorge de la Rosa, Julia Weber, Mathias Friedrich, +19

Nature Genetics

GeneticsMutagenesisTumor SuppressorCancer GeneticsGene Expression +4

PiggyBac transposon tools for recessive screening identify B-cell lymphoma drivers in mice

Julia Weber, Jorge de la Rosa, Carolyn Grove, +37

Nature Communications

Genome-wide transposon screening and quantitative insertion site sequencing for cancer gene discovery in mice

Mathias Friedrich, Lena Rad, Iraad F. Bronner, +15

Nature Protocols

BioinformaticsQuantitative Insertion SiteGenome-wide Transposon ScreeningTumor HeterogeneityMedicine +10