Valérie Steier

An Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead Discovery

Pawel Linke, Kwame Amaning, Melanie Maschberger et al. · SLAS DISCOVERY · 2015 · 88 citations · Full text

Discovery of 6-(2,4-Dichlorophenyl)-5-[4-[(3<i>S</i>)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7<i>H</i>-benzo[7]annulene-2-carboxylic acid (SAR439859), a Potent and Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen-Receptor-Positive Breast Cancer

Youssef El‐Ahmad, Michel Tabart, Frank Halley et al. · Journal of Medicinal Chemistry · 2019 · 80 citations · Full text

Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity

Salvador F. Ausar, Shaolong Zhu, Jessica Duprez et al. · Communications Biology · 2020 · 32 citations · Full text

KRAS G12C fragment screening renders new binding pockets

Magali Mathieu, Valérie Steier, Florence Fassy et al. · Small GTPases · 2021 · 22 citations · Full text

X-ray Crystallography, Drug Target, Engineering +18