Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

Stéphane Bressanelli, Licia Tomei, Alain Roussel, +5

Proceedings of the National Academy of Sciences

Virus StructureCrystal StructureViral ReplicationBiochemistryViral Polymerase Structure +13

A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy

Baptiste Ronan, Odile Flamand, Lionel Vescovi, +14

Nature Chemical Biology

Cell AutophagySignal TransductionCell TraffickingAutophagyLipophagy +8

Dengue Virus Type 1 Nonstructural Glycoprotein NS1 Is Secreted from Mammalian Cells as a Soluble Hexamer in a Glycosylation-Dependent Fashion

Marie Flamand, Françoise Mégret, Magali Mathieu, +3

Journal of Virology

Molecular Shape and Medicinal Chemistry: A Perspective

Anthony Nicholls, Georgia B. McGaughey, Robert P. Sheridan, +10

Journal of Medicinal Chemistry

EngineeringMolecular ShapeBiomedical EngineeringPharmaceutical ChemistryMolecular Design +15

Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion

Magali Mathieu

The EMBO Journal

Virus StructureViral ReplicationBiochemistryNatural SciencesAtomic Structure +6

Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 angstroms resolution: a spiral fold defines the CoA-binding pocket.

Christian K. Engel, Magali Mathieu, Johan Zeelen, +2

The EMBO Journal

Crystal StructureBiochemistryCoa-binding PocketNatural SciencesProtein X-ray Crystallography +7

Structure of the Sec7 domain of the Arf exchange factor ARNO

Jacqueline Cherfils, Julie Ménétrey, Magali Mathieu, +5

Nature

Quantum Field TheoryPhysicsSec7 Domain

Structural Basis for Human Monoglyceride Lipase Inhibition

Thomas Bertrand, Franck Augé, Jacques Houtmann, +8

Journal of Molecular Biology

Lipid ScienceLipidsBiochemistryStructural Basis

Selective Inhibition of Mutant Isocitrate Dehydrogenase 1 (IDH1) via Disruption of a Metal Binding Network by an Allosteric Small Molecule

Gejing Deng, Junqing Shen, Ming Yin, +23

Journal of Biological Chemistry

N-terminal arm exchange is observed in the 2.15 Å crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa

Didier Nurizzo, Maria-Chiara Silvestrini, Magali Mathieu, +7

Structure

å Crystal StructureBiochemistryReactive Nitrogen SpecieNitrosative StressPseudomonas Aeruginosa +6