Optimization of the in Vitro Cardiac Safety of Hydroxamate-Based Histone Deacetylase Inhibitors

Michael D. Shultz, Xueying Cao, Christine Chen, +34

Journal of Medicinal Chemistry

Many Hdac InhibitorsCardiovascular ToxicityMedicinal ChemistryHeart FailureHdac Inhibitors +13

Carp Toll-like receptor 8 (Tlr8): An intracellular Tlr that recruits TIRAP as adaptor and activates AP-1 pathway in immune response

Shijuan Shan, Rongrong Liu, Lei Jiang, +4

Fish & Shellfish Immunology

InflammationToll-like ReceptorsMolecular ImmunologyAutoimmune DiseaseAp-1 Pathway +9

Overexpression of CDK7 is associated with unfavourable prognosis in oral squamous cell carcinoma

Lei Jiang, Rong Huang, Yaping Wu, +7

Pathology

Tumor BiologyMedicinePathologyUnfavourable PrognosisCancer Biology +5

Conformational Refinement of Hydroxamate-Based Histone Deacetylase Inhibitors and Exploration of 3-Piperidin-3-ylindole Analogues of Dacinostat (LAQ824)

Young Shin Cho, Lewis Whitehead, Jianke Li, +17

Journal of Medicinal Chemistry

Hdac InhibitorsChemoprevention StrategyMolecular BiologyChemical BiologyPharmaceutical Chemistry +14

Immune landscape and subtypes in primary resectable oral squamous cell carcinoma: prognostic significance and predictive of therapeutic response

Pengfei Diao, Yue Jiang, Yuanyuan Li, +17

Journal for ImmunoTherapy of Cancer

The design, synthesis and structure–activity relationships of novel isoindoline-based histone deacetylase inhibitors

Michael D. Shultz, Jianmei Fan, Christine Chen, +20

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryBiochemistryMedicineNatural Sciences +8

Development and validation of a seven‐immune‐feature‐based prognostic score for oral squamous cell carcinoma after curative resection

Chen Zhou, Pengfei Diao, Yaping Wu, +10

International Journal of Cancer

Surgical OncologyCurative ResectionImmunologyImmunoeditingPathology +19

Analysis of diversity and relationships among orchardgrass (Dactylis glomerata L.) accessions using start codon-targeted markers

Lei Jiang, Xiaole Qi, Xinhua Zhang, +3

Genetics and Molecular Research

Molecular characterization and functional analysis of interferon regulatory factor 9 (<i>irf9</i>) in common carp <scp><i>Cyprinus carpio</i></scp>: a pivotal molecule in the Ifn response against pathogens

Yaoyao Zhu, Shijuan Shan, Hanxiao Feng, +4

Journal of Fish Biology

Integrated Gene Expression and Methylation Analyses Identify DLL3 as a Biomarker for Prognosis of Malignant Glioma

Aierpati Maimaiti, Xixian Wang, Yujun Hao, +5

Journal of Molecular Neuroscience

Neuro-oncologyGliomaMedicineEpigenetic ChangeMalignant Glioma +10