Lindsay A. Devine

Identification of <i>N</i>-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1<i>H</i>-pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design

Paul G. Wyatt, Andrew Woodhead, Valério Berdini et al. · Journal of Medicinal Chemistry · 2008 · 341 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Fragment-Based Discovery of the Pyrazol-4-yl Urea (AT9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity

Steven Howard, Valério Berdini, John A. Boulstridge et al. · Journal of Medicinal Chemistry · 2008 · 331 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14

Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Adrian L. Gill, Martyn Frederickson, Anne Cleasby et al. · Journal of Medicinal Chemistry · 2004 · 188 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Detection of Ligands from a Dynamic Combinatorial Library by X‐ray Crystallography

Miles Congreve, Deborah Davis, Lindsay A. Devine et al. · Angewandte Chemie International Edition · 2003 · 97 citations · Full text

Life Sciences, Chemistry, Medicinal Chemistry +16

Potent, Selective Inhibitors of Fibroblast Growth Factor Receptor Define Fibroblast Growth Factor Dependence in Preclinical Cancer Models

Matthew Squires, George A. Ward, Gordan Saxty et al. · Molecular Cancer Therapeutics · 2011 · 32 citations · Full text

Medicine, Oncology, Pharmacology +15