Andrew Woodhead

Identification of <i>N</i>-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1<i>H</i>-pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design

Paul G. Wyatt, Andrew Woodhead, Valério Berdini et al. · Journal of Medicinal Chemistry · 2008 · 337 citations · Full text

Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design

Andrew Woodhead, Hayley C. Angove, Maria G. Carr et al. · Journal of Medicinal Chemistry · 2010 · 258 citations

Pharmaceutical Science, Novel Inhibitor, Drug Target +19

Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency

Christopher W. Murray, Maria G. Carr, Owen Callaghan et al. · Journal of Medicinal Chemistry · 2010 · 185 citations · Full text

Molecular Docking, High Ligand Efficiency, Medicinal Chemistry +15

Identification of Novel p38α MAP Kinase Inhibitors Using Fragment-Based Lead Generation

Adrian L. Gill, Martyn Frederickson, Anne Cleasby et al. · Journal of Medicinal Chemistry · 2004 · 185 citations · Full text

Combinatorial Chemistry, Drug Target, Hit Identification +18

Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function

S. Saalau-Bethell, Andrew Woodhead, Gianni Chessari et al. · Nature Chemical Biology · 2012 · 111 citations · Full text

Virus Structure, Viral Replication, Signal Transduction +8