Inhibitory Effects of Antioxidants on Neonatal Rat Cardiac Myocyte Hypertrophy Induced by Tumor Necrosis Factor-α and Angiotensin II

Kazufumi Nakamura, Kazuo Fushimi, Hirosuke Kouchi, +4

Circulation

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

Weirui Guo, Yanbo Chen, Xiaohong Zhou, +18

Nature Structural & Molecular Biology

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisMolecular BiologyDegenerative PathologyProtein Misfolding +6

TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

Peng Wang, Jianwen Deng, Jie Dong, +12

PLoS Genetics

MitophagyMitochondrial DysfunctionGeneticsMolecular BiologyCell Death +15

A <i>Drosophila</i> model for TDP-43 proteinopathy

Yan Li, Payal Ray, Elizabeth J. Rao, +6

Proceedings of the National Academy of Sciences

Neurodegenerative DiseasesAmyotrophic Lateral SclerosisGeneticsExperimental NeuropathologyProtein Genetics +9

FUS Interacts with HSP60 to Promote Mitochondrial Damage

Jianwen Deng, Mengxue Yang, Yanbo Chen, +12

PLoS Genetics

MitophagyGeneticsCell DeathMolecular BiologyMolecular Genetics +14

Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5

Kazuo Fushimi, Payal Ray, Amar N. Kar, +3

Proceedings of the National Academy of Sciences

ApoptosisCell DeathPathologyCandidate Tumor SuppressorCancer Biology +15

RNA Helicase p68 (DDX5) Regulates <i>tau</i> Exon 10 Splicing by Modulating a Stem-Loop Structure at the 5′ Splice Site

Amar N. Kar, Kazuo Fushimi, Xiaohong Zhou, +6

Molecular and Cellular Biology

Rna ProcessingTranscriptional RegulationStem-loop StructureNatural SciencesGenetics +11

FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models

Jianwen Deng, Peng Wang, Xiaoping Chen, +5

Proceedings of the National Academy of Sciences

Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy

Kazuo Fushimi, Charles D. Long, Neha Jayaram, +3

Protein & Cell

Expression of human FUS protein in Drosophila leads to progressive neurodegeneration

Yanbo Chen, Mengxue Yang, Jianwen Deng, +14

Protein & Cell