A novel systemic inflammation response index (SIRI) for predicting the survival of patients with pancreatic cancer after chemotherapy

Qi Qi, Liping Zhuang, Yehua Shen, +7

Cancer

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

Bingyu Liu, Meng Zhang, Honglei Chu, +9

Nature Immunology

Signaling PathwayCell RegulationLys63-linked PolyubiquitinationNatural SciencesMolecular Biology +6

TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

Peng Wang, Jianwen Deng, Jie Dong, +12

PLoS Genetics

MitophagyMitochondrial DysfunctionGeneticsMolecular BiologyCell Death +15

E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1

Guanhua Song, Bingyu Liu, Zhihui Li, +6

Nature Immunology

K63-linked UbiquitinationViral ImmunityImmunologyImmune RegulationInnate Antiviral Immunity +8

TRIM26 Negatively Regulates Interferon-β Production and Antiviral Response through Polyubiquitination and Degradation of Nuclear IRF3

Peng Wang, Wei Zhao, Kai Zhao, +2

PLoS Pathogens

Viral ReplicationMolecular RegulationMolecular BiologyTranscriptional RegulationTranscription Factor Irf3 +19

Lipotoxicity-induced mtDNA release promotes diabetic cardiomyopathy by activating the cGAS-STING pathway in obesity-related diabetes

Xiu Mei, Kang Geng, Betty Yuen Kwan Law, +7

Cell Biology and Toxicology

Impact of antimicrobial stewardship managed by clinical pharmacists on antibiotic use and drug resistance in a Chinese hospital, 2010–2016: a retrospective observational study

Huaguang Wang, Han Wang, Xiaojia Yu, +13

BMJ Open

Insights into irradiation-affected structural evolution and mechanical behavior of amorphous carbon

Yeran Shi, Qiaosheng Xia, Mingda Xie, +7

Acta Materialia

Brain Tumor Stem-Like Cells Identified by Neural Stem Cell Marker CD15

Xinggang Mao, Xiang Zhang, Xiaoyan Xue, +6

Translational Oncology

Neuro-oncologyCell TherapySurface Marker Cd133Developmental BiologyTumor Innervation +13

Systemic inflammation response index (SIRI) predicts prognosis in hepatocellular carcinoma patients

Litao Xu, Shulin Yu, Liping Zhuang, +4

Oncotarget