Weirui Guo

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

Weirui Guo, Yanbo Chen, Xiaohong Zhou et al. · Nature Structural & Molecular Biology · 2011 · 306 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Molecular Biology +8

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

Nien‐Pei Tsai, Julia R. Wilkerson, Weirui Guo et al. · Cell · 2012 · 291 citations · Full text

Synaptic Plasticity, Proteasomal Degradation, Molecular Neuroscience +12

A <i>Drosophila</i> model for TDP-43 proteinopathy

Yan Li, Payal Ray, Elizabeth J. Rao et al. · Proceedings of the National Academy of Sciences · 2010 · 267 citations · Full text

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Genetics +11

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome

Jennifer Ronesi, Katie A. Collins, Seth A. Hays et al. · Nature Neuroscience · 2012 · 249 citations

Knockout Mouse, Molecular Physiology, Molecular Neuroscience +13

Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice

Kristen K. Ade, Yehong Wan, Harold C. Hamann et al. · Biological Psychiatry · 2016 · 83 citations · Full text

Neurobiological Mechanism, Striatal Circuit Abnormalities, Psychiatry +12