Jean-Noel Levy

Design and Synthesis of Tesirine, a Clinical Antibody–Drug Conjugate Pyrrolobenzodiazepine Dimer Payload

Arnaud Tiberghien, Jean-Noel Levy, Luke A. Masterson et al. · ACS Medicinal Chemistry Letters · 2016 · 161 citations · Full text

ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer–Containing Antibody–Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies

Michael Flynn, Francesca Zammarchi, Peter Tyrer et al. · Molecular Cancer Therapeutics · 2016 · 125 citations · Full text

Biodistribution of a benzoporphyrin derivative-monoclonal antibody conjugate in A549-tumor-bearing nude mice.

Frank N. Jiang, Anna Richter, A Jain et al. · PubMed · 1993 · 23 citations

Tumor Biology, Immunocytochemical Technique, A549-tumor-bearing Nude Mice +14

An optimised synthesis of SG3376, a non-cleavable antibody-drug conjugate pyrrolobenzodiazepine drug-linker

Arnaud Tiberghien, Stephen J. Gregson, Luke A. Masterson et al. · Tetrahedron Letters · 2017 · 12 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +8

Pre-Clinical Activity of Adct-301, a Novel Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies

Michael Flynn, Patrick van Berkel, Francesca Zammarchi et al. · Blood · 2014 · 10 citations