David Barford

Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF

Paul Wan, Mathew J. Garnett, S. Mark Roe et al. · Cell · 2004 · 2.8K citations · Full text

Oncogenic Mutations, Signal Transduction, Signaling Pathway +9

Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate

Annette Salmeen, Jannik N. Andersen, Michael P. Myers et al. · Nature · 2003 · 944 citations

Redox Signaling, Signal Transduction, Biochemistry +9

Development of “substrate-trapping” mutants to identify physiological substrates of protein tyrosine phosphatases

Andrew Flint, Tony Tiganis, David Barford et al. · Proceedings of the National Academy of Sciences · 1997 · 776 citations · Full text

Crystal Structure of Human Protein Tyrosine Phosphatase 1B

David Barford, Andrew Flint, Nicholas K. Tonks · Science · 1994 · 755 citations

Crystal Structure, Protein Function, Protein Assembly +13

Structural Basis for Phosphotyrosine Peptide Recognition by Protein Tyrosine Phosphatase 1B

Zongchao Jia, David Barford, Andrew Flint et al. · Science · 1995 · 581 citations