Stefano Annunziato

The shieldin complex mediates 53BP1-dependent DNA repair

Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra et al. · Nature · 2018 · 635 citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +4

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

Ewa Gogola, Alexandra A. Duarte, Julian R. de Ruiter et al. · Cancer Cell · 2018 · 379 citations · Full text

Parg Restores Parylation, Selective Loss, Medicine +4

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells

Marco Barazas, Stefano Annunziato, Stephen J. Pettitt et al. · Cell Reports · 2018 · 157 citations · Full text

BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance

Alexandra A. Duarte, Ewa Gogola, Norman Sachs et al. · Nature Methods · 2017 · 148 citations · Full text

Cancer-drug Resistance, Breast Cancer, Medicine +3

Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland

Stefano Annunziato, Sjors M. Kas, Micha Nethe et al. · Genes & Development · 2016 · 146 citations · Full text

Engineering, Immunology, Molecular Biology +19