Stefano Annunziato

The shieldin complex mediates 53BP1-dependent DNA repair

Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra et al. · Nature · 2018 · 660 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

Ewa Gogola, Alexandra A. Duarte, Julian R. de Ruiter et al. · Cancer Cell · 2018 · 385 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

The CST Complex Mediates End Protection at Double-Strand Breaks and Promotes PARP Inhibitor Sensitivity in BRCA1-Deficient Cells

Marco Barazas, Stefano Annunziato, Stephen J. Pettitt et al. · Cell Reports · 2018 · 162 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance

Alexandra A. Duarte, Ewa Gogola, Norman Sachs et al. · Nature Methods · 2017 · 152 citations · Full text

Medicine, Cancer Biology, Oncology +14

Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland

Stefano Annunziato, Sjors M. Kas, Micha Nethe et al. · Genes & Development · 2016 · 149 citations · Full text

Medicine, Molecular Genetics, Oncology +14