Isao Naguro

The roles of ASK family proteins in stress responses and diseases

Kazuki Hattori, Isao Naguro, Christopher Runchel et al. · Cell Communication and Signaling · 2009 · 203 citations · Full text

Requirement of Reactive Oxygen Species-dependent Activation of ASK1-p38 MAPK Pathway for Extracellular ATP-induced Apoptosis in Macrophage

Takuya Noguchi, Ken J. Ishii, Hisashi Fukutomi et al. · Journal of Biological Chemistry · 2008 · 193 citations · Full text

Mitophagy, Lipid Peroxidation, Apoptosis +20

The aspartyl protease DDI2 activates Nrf1 to compensate for proteasome dysfunction

Shun Koizumi, Taro Irie, Shoshiro Hirayama et al. · eLife · 2016 · 182 citations · Full text

Immunology, Proteasome, Cell Death +18

SOD1 as a Molecular Switch for Initiating the Homeostatic ER Stress Response under Zinc Deficiency

Kengo Homma, Takao Fujisawa, Naomi Tsuburaya et al. · Molecular Cell · 2013 · 137 citations · Full text

Reductive Stress, Signal Transduction, Molecular Regulation +11

ASK1 and ASK2 differentially regulate the counteracting roles of apoptosis and inflammation in tumorigenesis

Takayuki Iriyama, Kohsuke Takeda, Hiromi Nakamura et al. · The EMBO Journal · 2009 · 129 citations · Full text

Inflammation, Tumor Biology, Cell Regulation +9