Joseph A. Tino

An MTP Inhibitor That Normalizes Atherogenic Lipoprotein Levels in WHHL Rabbits

John R. Wetterau, Richard E. Gregg, Thomas Harrity et al. · Science · 1998 · 268 citations

Hyperlipidemia, Whhl Rabbits, Metabolic Syndrome +17

Discovery of 6-Fluoro-5-(<i>R</i>)-(3-(<i>S</i>)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4<i>H</i>)-yl)-2-methylphenyl)-2-(<i>S</i>)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1<i>H</i>-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers

Scott H. Watterson, George V. De Lucca, Qing Shi et al. · Journal of Medicinal Chemistry · 2016 · 142 citations · Full text

Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton’s Tyrosine Kinase (BTK)

Scott H. Watterson, Qingjie Liu, Myra Beaudoin Bertrand et al. · Journal of Medicinal Chemistry · 2019 · 104 citations · Full text

Tyrosine Kinase, Immunology, Quantitative Pharmacology +20

2-Hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors

James J. Li, Haixia Wang, Joseph A. Tino et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 89 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +8

Enhanced Gastrointestinal Motility with Orally Active Ghrelin Receptor Agonists

Soratree Charoenthongtrakul, Derek J. Giuliana, Kenneth Longo et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 60 citations