Myra Beaudoin Bertrand

Discovery of 6-Fluoro-5-(<i>R</i>)-(3-(<i>S</i>)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4<i>H</i>)-yl)-2-methylphenyl)-2-(<i>S</i>)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1<i>H</i>-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers

Scott H. Watterson, George V. De Lucca, Qing Shi et al. · Journal of Medicinal Chemistry · 2016 · 142 citations · Full text

Discovery of Branebrutinib (BMS-986195): A Strategy for Identifying a Highly Potent and Selective Covalent Inhibitor Providing Rapid in Vivo Inactivation of Bruton’s Tyrosine Kinase (BTK)

Scott H. Watterson, Qingjie Liu, Myra Beaudoin Bertrand et al. · Journal of Medicinal Chemistry · 2019 · 104 citations · Full text

Tyrosine Kinase, Immunology, Quantitative Pharmacology +20

Mild Conditions for Pd-Catalyzed Carboamination of <i>N</i>-Protected Hex-4-enylamines and 1-, 3-, and 4-Substituted Pent-4-enylamines. Scope, Limitations, and Mechanism of Pyrrolidine Formation

Myra Beaudoin Bertrand, Joshua D. Neukom, John P. Wolfe · The Journal of Organic Chemistry · 2008 · 99 citations · Full text

Stereoselective synthesis of N-protected pyrrolidines via Pd-catalyzed reactions of γ-(N-acylamino) alkenes and γ-(N-Boc-amino) alkenes with aryl bromides

Myra Beaudoin Bertrand, John P. Wolfe · Tetrahedron · 2005 · 74 citations

Engineering, Organic Chemistry, Pd-catalyzed Reactions +6

A Concise Stereoselective Synthesis of Preussin, 3-<i>e</i><i>pi</i>-Preussin, and Analogues

Myra Beaudoin Bertrand, John P. Wolfe · Organic Letters · 2006 · 63 citations · Full text