Martin Franke

Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions

Darío G. Lupiáñez, Katerina Kraft, Verena Heinrich et al. · Cell · 2015 · 2.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Formation of new chromatin domains determines pathogenicity of genomic duplications

Martin Franke, Daniel M. Ibrahim, Guillaume Andrey et al. · Nature · 2016 · 719 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Functional dissection of the Sox9–Kcnj2 locus identifies nonessential and instructive roles of TAD architecture

Alexandra Despang, Robert Schöpflin, Martin Franke et al. · Nature Genetics · 2019 · 340 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Deletions, Inversions, Duplications: Engineering of Structural Variants using CRISPR/Cas in Mice

Katerina Kraft, Sinje Geuer, Anja J. Will et al. · Cell Reports · 2015 · 237 citations · Full text

Life Sciences, Biotechnology, Genetics +17

Dynamic 3D chromatin architecture contributes to enhancer specificity and limb morphogenesis

Bjørt K. Kragesteen, Malte Spielmann, Christina Paliou et al. · Nature Genetics · 2018 · 213 citations · Full text

Life Sciences, Developmental Biology, Molecular Biology +16