Thomas W. Chittenden

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome<i>c</i>release in isolated mitochondria

Masashi Narita, Shigeomi Shimizu, Toshinori Ito et al. · Proceedings of the National Academy of Sciences · 1998 · 923 citations · Full text

Puma is an essential mediator of p53-dependent and -independent apoptotic pathways

John Jeffers, Evan Parganas, Youngsoo Lee et al. · Cancer Cell · 2003 · 868 citations · Full text

Tumor Biology, -Independent Apoptotic Pathways, Medicine +9

Induction of apoptosis by the Bcl-2 homologue Bak

Thomas W. Chittenden, Elizabeth A. Harrington, Rosemary O’Connor et al. · Nature · 1995 · 734 citations

Signal Transduction, Bcl-2 Homologue Bak, Cell Regulation +6

Aging and neurodegeneration are associated with increased mutations in single human neurons

Michael A. Lodato, Rachel E. Rodin, Craig L. Bohrson et al. · Science · 2017 · 636 citations · Full text

Increased Mutations, Aging, Genetics +16

A conserved domain in Bak, distinct from BH1 and BH2, mediates cell death and protein binding functions.

Thomas W. Chittenden, Cathy Flemington, Anne B. Houghton et al. · The EMBO Journal · 1995 · 490 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +10