Michael A. Lodato

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Menno P. Creyghton, Albert W. Cheng, G. Grant Welstead et al. · Proceedings of the National Academy of Sciences · 2010 · 4.4K citations · Full text

Histone Modifications, Epigenetic Change, Genetics +20

Aging and neurodegeneration are associated with increased mutations in single human neurons

Michael A. Lodato, Rachel E. Rodin, Craig L. Bohrson et al. · Science · 2017 · 636 citations · Full text

Increased Mutations, Aging, Genetics +16

Somatic mutation in single human neurons tracks developmental and transcriptional history

Michael A. Lodato, Mollie B. Woodworth, Semin Lee · Science · 2015 · 573 citations

Brain Development, Genetics, Genomic Mechanism +19

A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types

Marius Wernig, Christopher J. Lengner, Jacob H. Hanna et al. · Nature Biotechnology · 2008 · 436 citations · Full text

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Engineering +13

H2AZ Is Enriched at Polycomb Complex Target Genes in ES Cells and Is Necessary for Lineage Commitment

Menno P. Creyghton, Styliani Markoulaki, Stuart S. Levine et al. · Cell · 2008 · 337 citations · Full text

Chromatin, Es Cells, Lineage Plasticity +11