Rosemary O’Connor

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

Aileen M. Moloney, Rebecca J. Griffin, Suzanne Timmons et al. · Neurobiology of Aging · 2008 · 767 citations

Life Sciences, Molecular Biology, Neuroscience +17

Induction of apoptosis by the Bcl-2 homologue Bak

Thomas W. Chittenden, Elizabeth A. Harrington, Rosemary O’Connor et al. · Nature · 1995 · 734 citations

Life Sciences, Cell Biology, Molecular Biology +11

Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology

Rebecca J. Griffin, Aileen M. Moloney, Mary Kelliher et al. · Journal of Neurochemistry · 2005 · 461 citations

Life Sciences, Neurobiology, Neuroscience +17

Identification of Domains of the Insulin-Like Growth Factor I Receptor That Are Required for Protection from Apoptosis

Rosemary O’Connor, Andrea Kauffmann-Zeh, Yimao Liu et al. · Molecular and Cellular Biology · 1997 · 256 citations · Full text

Life Sciences, Cell Biology, Endocrinology +17

RACK1 Is an Insulin-like Growth Factor 1 (IGF-1) Receptor-interacting Protein That Can Regulate IGF-1-mediated Akt Activation and Protection from Cell Death

Patrick A. Kiely, Anagha Sant, Rosemary O’Connor · Journal of Biological Chemistry · 2002 · 151 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13