Aileen M. Moloney

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

Aileen M. Moloney, Rebecca J. Griffin, Suzanne Timmons et al. · Neurobiology of Aging · 2008 · 756 citations

Neurodegenerative Diseases, Alzheimer's Disease, Insulin Signalling +11

Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology

Rebecca J. Griffin, Aileen M. Moloney, Mary Kelliher et al. · Journal of Neurochemistry · 2005 · 453 citations

Cell Death, Neurochemical Biomarkers, Social Sciences +20

Iron Promotes the Toxicity of Amyloid β Peptide by Impeding Its Ordered Aggregation

Beinan Liu, Aileen M. Moloney, Sarah Meehan et al. · Journal of Biological Chemistry · 2010 · 217 citations · Full text

Amyloid β, Iron Metabolism, Molecular Biology +20

Akt signal transduction dysfunction in Parkinson's disease

Suzanne Timmons, Meghan F. Coakley, Aileen M. Moloney et al. · Neuroscience Letters · 2009 · 186 citations

Parkinson Disease, Neurochemical Biomarkers, Neurology +2

ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism

Tetsuro Murakami, Seung‐Pil Yang, Lin Xie et al. · Human Molecular Genetics · 2011 · 121 citations · Full text

Mutant Fus, Amyotrophic Lateral Sclerosis, Developmental Biology +14