Role of Intermolecular Forces in Defining Material Properties of Protein Nanofibrils

Tuomas P. J. Knowles, Anthony W. P. Fitzpatrick, Sarah Meehan, +4

Science

Supramolecular AssemblyEngineeringMolecular Self-assemblyNanostructured PolymerBiofabrication +17

Metastability of Native Proteins and the Phenomenon of Amyloid Formation

Andrew J. Baldwin, Tuomas P. J. Knowles, Gian Gaetano Tartaglia, +12

Journal of the American Chemical Society

Protein ChemistryProtein FunctionProtein AssemblyBiochemistryProtein Folding +13

The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures

Justin J. Yerbury, Stephen Poon, Sarah Meehan, +4

The FASEB Journal

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide

Priyanka Narayan, Ángel Orte, Richard W. Clarke, +7

Nature Structural & Molecular Biology

Protein FunctionBiochemistryProtein AssemblyProtein FoldingNatural Sciences +6

Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass

Tuomas P. J. Knowles, Wenmiao Shu, Glyn L. Devlin, +4

Proceedings of the National Academy of Sciences

Iron Promotes the Toxicity of Amyloid β Peptide by Impeding Its Ordered Aggregation

Beinan Liu, Aileen M. Moloney, Sarah Meehan, +7

Journal of Biological Chemistry

Amyloid βIron MetabolismMolecular BiologyNeurochemical BiomarkersPeptide Science +18

Amyloid Fibril Formation by Bovine Milk κ-Casein and Its Inhibition by the Molecular Chaperones α_S- and β-Casein

David C. Thorn, Sarah Meehan, Margaret Sunde, +6

Biochemistry

Structure and Properties of a Complex of α-Synuclein and a Single-Domain Camelid Antibody

Erwin J. De Genst, Tim Guilliams, Joke Wellens, +12

Journal of Molecular Biology

Single-domain Camelid AntibodyNatural SciencesImmunologyMolecular BiologyProtein Misfolding +5

Amyloid Fibril Formation by Lens Crystallin Proteins and Its Implications for Cataract Formation

Sarah Meehan, Yoke Berry, Ben F. Luisi, +3

Journal of Biological Chemistry

Mimicking phosphorylation of αB-crystallin affects its chaperone activity

Heath Ecroyd, Sarah Meehan, Joseph Horwitz, +5

Biochemical Journal

Protein AssemblyMolecular BiologyProtein RefoldingProtein FoldingChaperones +16