β-Cell Failure in Diet-Induced Obese Mice Stratified According to Body Weight Gain: Secretory Dysfunction and Altered Islet Lipid Metabolism Without Steatosis or Reduced β-Cell Mass

Marie‐Line Peyot, Émilie Pépin, Julien Lamontagne, +8

Diabetes

Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling

Christopher J. Nolan, Jack L. Leahy, Viviane Delghingaro‐Augusto, +13

Diabetologia

Insulin ResistanceObesityMetabolic SyndromeSystems BiologyBeta Cell Compensation +9

Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytes

Yves Mugabo, Shangang Zhao, Annegrit Seifried, +12

Proceedings of the National Academy of Sciences

Adipose Triglyceride Lipase Is Implicated in Fuel- and Non-fuel-stimulated Insulin Secretion

Marie‐Line Peyot, Claudiane Guay, Martin G. Latour, +10

Journal of Biological Chemistry

Glucagon-Like Peptide-1 Induced Signaling and Insulin Secretion Do Not Drive Fuel and Energy Metabolism in Primary Rodent Pancreatic β-Cells

Marie‐Line Peyot, Joshua P. Gray, Julien Lamontagne, +5

PLoS ONE

Obese Mice Lacking Inducible Nitric Oxide Synthase Are Sensitized to the Metabolic Actions of Peroxisome Proliferator–Activated Receptor-γ Agonism

Patrice Dallaire, Kerstin Bellmann, Mathieu Laplante, +11

Diabetes

Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of known inhibitors

José Iglesias, Julien Lamontagne, Heidi Erb, +8

Journal of Lipid Research

Metabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells

Yves Mugabo, Shangang Zhao, Julien Lamontagne, +6

Journal of Biological Chemistry

Metabolic RemodelingInsulin SignalingMetabolic SyndromePancreatic CancerExcess Fuels +16

Pioglitazone Acutely Reduces Insulin Secretion and Causes Metabolic Deceleration of the Pancreatic β-Cell at Submaximal Glucose Concentrations

Julien Lamontagne, Émilie Pepin, Marie‐Line Peyot, +6

Endocrinology

Voluntary running exercise prevents β-cell failure in susceptible islets of the Zucker diabetic fatty rat

Viviane Delghingaro‐Augusto, Simon Décary, Marie‐Line Peyot, +9

American Journal of Physiology-Endocrinology and Metabolism

Physical ActivityInsulin SignalingMetabolic SyndromeKinesiologyBody Composition +15