Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

Claudiane Guay, Janine K. Kruit, Sophie Rome, +14

Cell Metabolism

Diabetes DevelopmentDevelopmental BiologyMay ContributeDiabetesImmunology +7

Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes

Valeria Nesca, Claudiane Guay, Cécile Jacovetti, +5

Diabetologia

ObesityMetabolic SyndromeGeneticsDiabetesType 2 +12

Circular RNAs as novel regulators of β-cell functions in normal and disease conditions

Lisa Stoll, Jonathan Sobel, Adriana Rodriguez‐Trejo, +6

Molecular Metabolism

Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice

Audrey Jalabert, Guillaume Vial, Claudiane Guay, +13

Diabetologia

Extracellular MicrovesiclesCytoskeletonLipid-induced Insulin-resistant MusclesCellular PhysiologyInsulin Signaling +14

A Role for ATP-Citrate Lyase, Malic Enzyme, and Pyruvate/Citrate Cycling in Glucose-induced Insulin Secretion

Claudiane Guay, S.R. Murthy Madiraju, Alexandre Aumais, +2

Journal of Biological Chemistry

Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells

Claudiane Guay, Véronique Menoud, Sophie Rome, +1

Cell Communication and Signaling

Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling

Christopher J. Nolan, Jack L. Leahy, Viviane Delghingaro‐Augusto, +13

Diabetologia

Insulin ResistanceObesityMetabolic SyndromeSystems BiologyBeta Cell Compensation +9

A circular RNA generated from an intron of the insulin gene controls insulin secretion

Lisa Stoll, Adriana Rodriguez‐Trejo, Claudiane Guay, +18

Nature Communications

Postnatal β-cell maturation is associated with islet-specific microRNA changes induced by nutrient shifts at weaning

Cécile Jacovetti, Scot J. Matkovich, Adriana Rodriguez‐Trejo, +2

Nature Communications

Adipose Triglyceride Lipase Is Implicated in Fuel- and Non-fuel-stimulated Insulin Secretion

Marie‐Line Peyot, Claudiane Guay, Martin G. Latour, +10

Journal of Biological Chemistry