Miranda M.C. van der Lee

Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody–Drug Conjugate SYD985

Ronald C. Elgersma, Ruud G. E. Coumans, Tijl Huijbregts et al. · Molecular Pharmaceutics · 2015 · 214 citations · Full text

Molecular Biology, Duocarmycin 3B, Pharmaceutical Chemistry +16

The Preclinical Profile of the Duocarmycin-Based HER2-Targeting ADC SYD985 Predicts for Clinical Benefit in Low HER2-Expressing Breast Cancers

Miranda M.C. van der Lee, Patrick G. Groothuis, Ruud Ubink et al. · Molecular Cancer Therapeutics · 2015 · 208 citations

Breast Oncology, Immunology, Pathology +20

β-Arrestin Recruitment Assay for the Identification of Agonists of the Sphingosine 1-Phosphate Receptor EDG1

Miranda M.C. van der Lee, Maaike Bras, Chris J. van Koppen et al. · SLAS DISCOVERY · 2008 · 53 citations · Full text

A Platform for the Generation of Site-Specific Antibody–Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines

Ruud G. E. Coumans, G.J.A. Ariaans, Henri Spijker et al. · Bioconjugate Chemistry · 2020 · 52 citations · Full text

β-Arrestin Recruitment and G Protein Signaling by the Atypical Human Chemokine Decoy Receptor CCX-CKR

Anne O. Watts, Folkert Verkaar, Miranda M.C. van der Lee et al. · Journal of Biological Chemistry · 2013 · 49 citations · Full text