Henri Spijker

Design, Synthesis, and Evaluation of Linker-Duocarmycin Payloads: Toward Selection of HER2-Targeting Antibody–Drug Conjugate SYD985

Ronald C. Elgersma, Ruud G. E. Coumans, Tijl Huijbregts et al. · Molecular Pharmaceutics · 2015 · 219 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Preclinical Profile of the HER2-Targeting ADC SYD983/SYD985: Introduction of a New Duocarmycin-Based Linker-Drug Platform

Wim H.A. Dokter, Ruud Ubink, Miranda van der Lee et al. · Molecular Cancer Therapeutics · 2014 · 163 citations · Full text

Pharmacy, Oncology, Pharmacology +17

Synthesis and assembly behavior of nucleobase‐functionalized block copolymers

Henri Spijker, A. J. Dirks, Jan C. M. van Hest · Journal of Polymer Science Part A Polymer Chemistry · 2006 · 63 citations · Full text

Natural Sciences, Chemistry, Materials Science +17

Atom Transfer Radical Polymerization of Adenine, Thymine, Cytosine, and Guanine Nucleobase Monomers

Henri Spijker, Floris L. van Delft, Jan C. M. van Hest · Macromolecules · 2007 · 63 citations

Pharmacy, Chemistry, Nucleic Acid Biochemistry +15

A Platform for the Generation of Site-Specific Antibody–Drug Conjugates That Allows for Selective Reduction of Engineered Cysteines

Ruud G. E. Coumans, G.J.A. Ariaans, Henri Spijker et al. · Bioconjugate Chemistry · 2020 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmaceutics +17