Christopher W. West

Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels

Ken McCormack, Sonia Santos, Mark L. Chapman et al. · Proceedings of the National Academy of Sciences · 2013 · 243 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

Aristos J. Alexandrou, Adam R. Brown, Mark L. Chapman et al. · PLoS ONE · 2016 · 194 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Differential Inhibition of Inducible T Cell Cytokine Secretion by Potent Iron Chelators

Stewart Leung, April Holbrook, Beverly King et al. · SLAS DISCOVERY · 2005 · 97 citations · Full text

Life Sciences, Immunology, Pharmacology +15

Discovery of Clinical Candidate 4-[2-(5-Amino-1<i>H</i>-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-<i>N</i>-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of Na_V1.7

Nigel A. Swain, D. V. Batchelor, Serge Beaudoin et al. · Journal of Medicinal Chemistry · 2017 · 83 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

Binding energy of solvated electrons and retrieval of true UV photoelectron spectra of liquids

Junichi Nishitani, Yoichi Yamamoto, Christopher W. West et al. · Science Advances · 2019 · 71 citations · Full text

Natural Sciences, Chemistry, Physics +13