Lucía Regales

Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer

Lucía Regales, Yixuan Gong, Ronglai Shen et al. · Journal of Clinical Investigation · 2009 · 366 citations · Full text

Medicine, Oncology, Pharmacology +17

Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer

Martin L. Sos, Stefanie Fischer, Roland T. Ullrich et al. · Proceedings of the National Academy of Sciences · 2009 · 256 citations · Full text

Medicine, Genetics, Oncology +17

Development of New Mouse Lung Tumor Models Expressing EGFR T790M Mutants Associated with Clinical Resistance to Kinase Inhibitors

Lucía Regales, Marissa N. Balak, Yixuan Gong et al. · PLoS ONE · 2007 · 124 citations · Full text

Medicine, Molecular Biology, Oncology +15

Identification and Functional Validation of a 5′ Upstream Regulatory Sequence in the Human Tyrosinase Gene Homologous to the Locus Control Region of the Mouse Tyrosinase Gene

Lucía Regales, Patricia Giraldo, Ángel García-Díaz et al. · Pigment Cell Research · 2003 · 38 citations

Life Sciences, Biology, Genetics +17

Rapamycin Prevents the Development and Progression of Mutant Epidermal Growth Factor Receptor Lung Tumors with the Acquired Resistance Mutation T790M

Shigeru Kawabata, Jose Mercado-Matos, M. Christine Hollander et al. · Cell Reports · 2014 · 30 citations · Full text

Medicine, Oncology, Pharmacology +17