Concepedia

Eliane Schweizer

ES

4

Publications

135

Citations

4

H-Index

2003

Active since

Affiliations

Roche (Switzerland)(Current)

ETH Zurich

Johannes Gutenberg University Mainz

Eliane Schweizer is an author at Roche (Switzerland) specializing in medicinal chemistry, chemical biology, and drug discovery.

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Publications per year

2003–2006

4

Publications

4

A Fluorine Scan at the Catalytic Center of Thrombin: CF, COH, and COMe Bioisosterism and Fluorine Effects on p<i>K</i><sub>a</sub> and log <i>D</i> Values

Eliane Schweizer, Anja Hoffmann‐Röder, K. Schärer et al. · ChemMedChem · 2006 · 58 citations

Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors

Eliane Schweizer, Anja Hoffmann‐Röder, Jacob Olsen et al. · Organic & Biomolecular Chemistry · 2006 · 31 citations

, , +24

Mapping the Fluorophilicity of a Hydrophobic Pocket: Synthesis and Biological Evaluation of Tricyclic Thrombin Inhibitors Directing Fluorinated Alkyl Groups into the P Pocket

Anja Hoffmann‐Röder, Eliane Schweizer, J. Egger et al. · ChemMedChem · 2006 · 28 citations

Bisubstrate Inhibitors for the Enzyme Catechol <i>O</i>‐Methyltransferase (COMT): Dramatic Effects of Ribose Modifications on Binding Affinity and Binding Mode

C. Lerner, Romain Siegrist, Eliane Schweizer et al. · Helvetica Chimica Acta · 2003 · 18 citations

, , +23

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