Jacob Olsen - Concepedia

Author

Jacob Olsen

ETH Zurich ORCID

Also Known As

J. A. Olsen, J.A Olsen, J.A. Olsen, Jacob A. Olsen, Jacob Olsen, Jacob A. Olsen, Martinez, Robert R., Olsen, J.A.

Publications

752

Citations

H-Index

Concepts

All Affiliations

ETH Zurich Roche (Switzerland)Johannes Gutenberg University Mainz Technical University of Denmark

About

Jacob Olsen is an author at ETH Zurich specializing in biochemistry, natural sciences, and organic chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Natural Sciences	3	3	135
2	Biochemistry	3	3	135
3	Engineering	2	2	104
4	Medicine	2	2	49
5	Biomolecular Engineering	1	1	89

Jacob Olsen

Publications

749

Citations

H-Index

Page 1

	Year	Citations
A Fluorine Scan of Thrombin Inhibitors to Map the Fluorophilicity/Fluorophobicity of an Enzyme Active Site: Evidence for CF⋅⋅⋅CO Interactions Jacob Olsen, David W. Banner, Paul Seiler, Angewandte Chemie International Edition	2003	199
Fluorine Interactions at the Thrombin Active Site: Protein Backbone Fragments HC<sub>α</sub>CO Comprise a Favorable CF Environment and Interactions of CF with Electrophiles Jacob Olsen, David W. Banner, Paul Seiler, ChemBioChem	2004	148
A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pK<sub>a</sub>and binding affinity and evidence for intermolecular C–F⋯CN interactions Jacob Olsen, Paul Seiler, Björn Wagner, Organic & Biomolecular Chemistry	2004	95
Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers Jacob Olsen, Rune Severinsen, Torsten B. Rasmussen, Bioorganic & Medicinal Chemistry Letters Bioorganic ChemistryEngineeringBiochemistryNatural SciencesOrganic Chemistry	2002	89
A Fluorine Scan of Thrombin Inhibitors to Map the Fluorophilicity/Fluorophobicity of an Enzyme Active Site: Evidence for CF⋅⋅⋅CO Interactions Jacob Olsen, David W. Banner, Paul Seiler, Angewandte Chemie	2003	79
A Fluorine Scan at the Catalytic Center of Thrombin: CF, COH, and COMe Bioisosterism and Fluorine Effects on p<i>K</i><sub>a</sub> and log <i>D</i> Values Eliane Schweizer, Anja Hoffmann‐Röder, K. Schärer, ChemMedChem	2006	58
Multipolar interactions in the D pocket of thrombin: large differences between tricyclic imide and lactam inhibitors Eliane Schweizer, Anja Hoffmann‐Röder, Jacob Olsen, Organic & Biomolecular Chemistry Pharmaceutical SciencePeptide SciencePharmacotherapyChemical BiologyPharmaceutical Chemistry	2006	31
Identification of potent and broad-Spectrum antibiotics from SAR studies of a synthetic vancomycin analogue Kateri A. Ahrendt, Jacob Olsen, Masahiro Wakao, Bioorganic & Medicinal Chemistry Letters Sar StudiesAntibioticsMedicineAntibacterial AgentAntimicrobial Chemotherapy	2003	18
A comparative analysis of computer-aided design team performance with collaboration software K. L. Eves, John L. Salmon, Jacob Olsen, Computer-Aided Design and Applications	2018	17
Combinatorial Solid-Phase Synthesis of Hapalosin Mimetics Jacob Olsen, Knud J. Jensen, John Nielsen Journal of Combinatorial Chemistry Materials ScienceCyclic Depsipeptide HapalosinMedicinal ChemistryCombinatorial ChemistryBioorganic Chemistry	2000	15

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