Jacob Olsen

A Fluorine Scan of Thrombin Inhibitors to Map the Fluorophilicity/Fluorophobicity of an Enzyme Active Site: Evidence for CF⋅⋅⋅CO Interactions

Jacob Olsen, David W. Banner, Paul Seiler et al. · Angewandte Chemie International Edition · 2003 · 199 citations

Fluorine Interactions at the Thrombin Active Site: Protein Backbone Fragments HC_αCO Comprise a Favorable CF Environment and Interactions of CF with Electrophiles

Jacob Olsen, David W. Banner, Paul Seiler et al. · ChemBioChem · 2004 · 148 citations

A fluorine scan of the phenylamidinium needle of tricyclic thrombin inhibitors: effects of fluorine substitution on pK_aand binding affinity and evidence for intermolecular C–F⋯CN interactions

Jacob Olsen, Paul Seiler, Björn Wagner et al. · Organic & Biomolecular Chemistry · 2004 · 95 citations

Synthesis of new 3- and 4-substituted analogues of acyl homoserine lactone quorum sensing autoinducers

Jacob Olsen, Rune Severinsen, Torsten B. Rasmussen et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 89 citations

Bioorganic Chemistry, Engineering, Biochemistry +6

A Fluorine Scan of Thrombin Inhibitors to Map the Fluorophilicity/Fluorophobicity of an Enzyme Active Site: Evidence for CF⋅⋅⋅CO Interactions

Jacob Olsen, David W. Banner, Paul Seiler et al. · Angewandte Chemie · 2003 · 79 citations